PRODUCT RANGE  
 
 
Select the country of your choice
 
INDIA NEPAL
India Nepal
   
BANGLADESH PHILIPPINES
Bangladesh Philippines
   
OMAN BHUTAN
Oman Bhutan
Antimicrobials & Antibiotics
 
  Back »
Feed Additives
 
  • Calfosvet
  • Calfosvet D.S. +
  • Grogold
  • Gromin-SE
  • Lifer
  • Profimin Forte
  • Toxiliv
  • Vetral
  • Vets Cu-Co
Calfosvet DOWNLOAD BROCHURE
The best oral calcium in homogenous suspension for better growth and productivity.

Nutritional value per 100 ml.
Calcium 1700 mg
Phosphorus 850 mg
Vitamin D3 8000 IU
Vitamin B12 100mcg
Carbohydrates 40000 mg

Salient features
  • Calfosvet provides optimum amount of calcium and phosphorus for faster growth and skeletal integrity.
  • Calfosvet provides vitamin B12 for increased appetite and growth.
  • Calfosvet provides vitamin D3 for better assimilation of calcium and phosphorus.
  • Calfosvet increases milk, egg and meat production.

Calcium is the most abundant mineral element in the body; ~98% functions as a structural component of bones and teeth. (Calcium and phosphorus in bones are always in a ratio of 2:1). The remaining 2% is distributed in extracellular fluids and soft tissues and is involved in such vital functions as blood clotting, membrane permeability, muscle contraction, transmission of nerve impulses, cardiac regulation, secretion of certain hormones, and activation and stabilization of certain enzymes.

Calfosvet
When cattle are fed roughages produced on calcium-low soils, or when finishing cattle are fed high-grain diets with limited nonlegume roughage, a calcium deficiency may develop.

Phosphorus about 80% of the phosphorus in the body is found in the bones and teeth, with the remainder distributed among the soft tissues. Adequate phosphorus is required for optimal performance in growth, reproduction, and lactation. In a phosphorus deficiency, reduced growth and inefficiency of feed conversion, decreased appetite, impaired reproduction, reduced milk production, and weak, fragile bones can be expected..

Vitamin D3 is important for proper bone growth and ossification, deficiency may lead to rickets, stiffness, weak & bent bones & posterior paralysis. Lowered Ca and P in the blood serum, cessation of growth, and weaker bones result from vitamin D deficiency in the growing calf.

Vitamin B12 is necessary for the formation and maturation of red blood cells and the synthesis of DNA (deoxyribonucleic acid), which is the genetic material of cells. Because vitamin B12 is necessary for the formation of mature blood cells, deficiency of this vitamin can result in anemia. The anemia is characterized by abnormally large red blood cells (macrocytes) and white blood cells with abnormal nuclei.
Vitamin B12 is also necessary for normal nerve functions.
Neonatal pigs fed diet low in vitamin B12 show hyperirritability, voice failure, pain and incoordination in the hindquarters.

Indications
  • To strengthen bones and egg shell.
  • For faster growth and to increase hatchability.
  • To prevent and control rickets, osteomalacia, osteoporosis, ruffed feathers, pica, stiffgait, muscular weakness, haemogrloinuria, (it is the condition when haemoglobin is filtered by the kidneys and is released in the urine, giving urine a red colour), anemia and thin shelled eggs.

Dosage
Cattle and Horse 100 ml daily
Calf, Sheep and Dog 10-20 ml twice daily.
Poultry  
Chicks 3.0 ml per liter of drinking water
Growers & Broilers 3.5 ml per liter of drinking water
Layers & Breeders 4.0 ml per liter of drinking water

Presentation
500ml, 1 lt., 2 lt., 5 lt. and 10 lt.

Note
Requirement of calcium and phosphorus is more during production, reproduction and growth. Extra calcium and phosphorus is required from outside source for skeletal development in pregnant and growing animals and in layers for egg shell formation. Additionaly vitamin D3 is also required for proper utilization of calcium and phosphorus.

Some common conditions caused by nutritional deficiency of calcium:
  • Milk fever
    Milk fever is characterized by low blood calcium and paralysis and is usually seen within 48 hr after calving in cows beyond their first lactation. High-calcium intake during the dry period increases the incidence; limiting calcium intake before calving but increasing it at calving time decreases the incidence.
  • Osteomalacia
    Osteomalacia is characterized by weak, brittle bones that may fracture when stressed, can develop after demineralization of the bones of aged animals. Feeding a diet low in calcium to lactating cows over a long period of time may cause a depletion of calcium and phosphorus, resulting in fragile, easily fractured bones plus decreased milk production, without affecting calcium level in the milk produced.
  • Rickets
    Rickets is characterized by improper calcification of the organic matrix of bone, which results in weak, soft bones that lack density. Signs include swollen, tender joints; enlarged bone ends; an arched back; stiffness of the legs; and development of beads on the ribs. Rickets is a disease of young animals and may be caused by deficiencies of calcium, phosphorus, or vitamin D.
Calfosvet D.S. + DOWNLOAD BROCHURE
Double strength. With additional advantages of Biotin & Protein hydrolysate

Nutritional value per 100 ml.
Calcium : 3500mg
Phosphorus : 1750mg
Vitamin D3 : 17500I.U.
Vitamin B12 : 200mcg
Carbohydrates : 50000mg
Biotin : 400mcg
Protein Hydrolysate : 1000mg

CALFOSVET DS + is the double strength liquid feed, processed in purified water with best absorbable calcium, phosphorus & stabilized vitamins D3 & B12 enriched with biotin, protein hydrolysate (amino acids) and carbohydrates.

Biotin
  • Biotin is a functional constituent of various enzyme system necessary to prevent fatty liver & kidney syndromes.
  • Biotin prevents perosis in chicks & improves hatchability.
  • Biotin has a significant effect on carbohydrate metabolism fatty acid synthesis & amino acid deamination.
  • Biotin is associated with formation of hoof & horn as it is necessary for synthesis of keratin a hard structure protein.
  • Biotin is associated with the resolution of brittle hoof & horn tissue.
  • Biotin plays a key role in the synthesis of glucose (imp. Energy source), protein & fat hence increases milk yield.

Calfosvet D.S. +

Protein hydrolysate

It is a mixture of amino acids prepared by splitting a protein with acid, alkali or enzyme; used as a nutrient replenisher. It also improves nitrogen retention.

Calcium is the most abundant mineral element in the body about 98% functions as a structural component of bones & Teeth. The remaining 2% is distributed in extra cellular fluid & soft tissues & is involved in such vital functions as blood clotting, membrane permeability, muscle contraction, transmission of nerve impulses, cardiac regulation, secretion of certain hormones & activation and stabilization of certain enzymes. The total ration should provide a calcium phosphorus ratio of 2:1.

Phosphorus about 80% of the phosphorus in the body is found in the bones & teeth with the remainder distributed among the soft tissue. Adequate phosphorus is required for optimal performance in growth, reproduction and lactation.

Vitamin D3 is important for proper bone growth & ossification. A major function & possibly the sole function of Vitamin D is related to its role in the intestinal & cellular absorption of calcium. Calcium, Phosphorus & Vitamin D are closely interrelated physiologically.

Vitamin B12 is required for growth, hemoglobin, red blood cell formation, embryonic development & feathering in poultry. B12 is necessary for the formation and maturation of RBC & synthesis of DNA which is genetic material of cells. B12 is also necessary for normal nerve functions. .

Carbohydrates: The principal function of Carbohydrates in the form of glucose & glycogen is to furnish energy for the body. More them 50% of the energy value of the diet is provided by the Carboydrates. Certain products of Carbohydrate metabolism (in Kreb cycle) are absolutely essential for oxidation of fats & proteins. Some Carboydrates have highly specific functions eq. ribose in the nucleo proteins (in RNA, DNA, ATP) etc glucose in certain lipids & the lactose in milk. The excess of carbohydrate intake if any is utilized for the transformation of fats or even for the carbon skeleton of proteins.

Feeding Rate:
Cattle & Horse: 50-100 ml daily
Calf & Dog: 10-20 ml daily

Presentation:
1 ltr. & 5 ltr.

Notes
Feed Additives for Dairy Cattle
Feeding high producing cows continues to challenge dairy farmers & nutritionists. Also dairy profit margins vary as milk prices & feed costs shift yearly. Feed costs represent the largest input cost to produce milk. (estimated to be 35 to 50 percent).
Feed additives are group of feed ingredients that can cause a desired animals response in a non nutrients role such as pH shift, growth, or metabolic modifier.

Dairy Managers must evaluate such feed additive, on the “4R” approach:
  • Anticipated response
  • Economic return
  • Available research
  • Field response

Feed Manufacturer should add an addition “3Rs” when selecting feed additives:
  • Reliability
  • Repeatability
  • Relativity

Milk Fever: is characterized by low blood calcium and paralysis & is usually seen within 48 hrs after calving in cows beyond their first lactation. High calcium intake during the dry period increases the incidence; limiting calcium intake before calving but increasing it at calving time decrease the incidence.

Requirement of Calcium & Phosphorus is more during, production, reproduction & growth. Extra calcium & phosphorus is required from outside source for skeletal, development in pregnant & growing animals & in layers for egg shell formation. Calcium & Phosphorus also plays important roles in the body essential for gestation & lactation.
Grogold DOWNLOAD BROCHURE
Millennium product
Grogold for better immunity, optimum production and better FCR


Grogold is multi-enzyme feed supplement, complex with essential amino-acids, vitamins and minerals for optimum productivity, better feed conversion ratio (FCR) and to improve immunity.

Formulation
Enzymes phytase, papain and protease
Aminoacids methionine, lysine and protein hydrolysate (mixture of amino acids)
Vitamins vitamin-A, D3, E and Niacin
Fatty acid linoleic acid
Minerals calcium, phosphorus, manganese and selenium

Salient features
  • Grogold provides essential enzymes for proper utilization of protein, minerals, vitamins & to improve F.C.R. (feed conversion ratio)
  • Grogold provides essential amino acids & fatty acid to strengthen the immunity.
  • Grogold provides various minerals & vitamins to obtain the optimum productivity.
  • The supplementation of Grogold can increase the assimilation efficiency of phytate phosphorus.
  • Grogold ensures faster and uniform weight gain.
  • Grogold helps in stresful conditions.
  • Grogold reduce mortality.


Grogold
Enzymes in Grogold
Grogold contains Phytase enzyme capable of breaking down phytates in feeds to release inorganic phosphorus & inositol as well as protein, aminoacids, trace minerals and other nutrients chelated with phytates. Thus phytase can reduce or eliminate the supplementation of inorganic phosphorus in feeds for monogastric animals & improve the utilization efficiency of these nutrients contained in feed stuff. As much as 90% of the total phosphorus in cereals & oil seeds can be locked up in the form of phytate, which is virtually indigestible form of phosphorus in plants used in animals feed.

Non ruminants lack sufficient intestinal phytase, by adding the enzyme to the diet, more phosphorus becomes available to the animal, which lowers the amount of supplemental phosphorus required and the amount that goes undigested. Papain and protease in Grogold are digestive enzymes, proteolytic in nature, hence improves the digestion and productivity.

Aminoacids in Grogold
Aminoacids are essential to produce, maintain and strengthen the immunity and blood formation. Protein hydrolysate  a mixture of amino acids prepared by splitting a protein with acid, alkali, or enzyme, used as a nutrient replenisher. Lysine (Essential aminoacid) Ensures adequate calcium absorption and maintains a proper nitrogen balance in adults; helps form collagen (which makes up cartilage and connective tissue); aids in the production of antibodies. Methionine (Essential aminoacid) is a powerful anti-oxidant and a good source of sulfur, which prevents disorders of the hair, skin, and nails, assists the breakdown of fats, thus helping to prevent a buildup of fat in the liver and arteries, that might obstruct blood flow to the brain, heart, and kidneys; helps to detoxify harmful agents such as lead and other heavy metals; helps diminish muscle weakness; prevents brittle hair; protects against the affects of radiation

Fatty acid in Grogold
Linoleic acid shown to improve feed efficiency, decrease body fat, and increase lean tissue in animals and essential for the production of immune cells.

Vitamins in Grogold
Vitamin A deficiency may lead to reproductive disorders, disturbances of the eye & epithelial tissue of respiratory, reproductive, nervous, urinary and gastrointestinal. system. Vitamin D is important for proper bone growth and ossification which may lead to rickets, stiffness, weak & bent bones & posterior paralysis. Vitamin Et is necessary for fertility. It also acts as an antioxidant. Deficiency causes muscular dystrophy, infertility. Vitamin E deficiency produces encephalomalacia, exudative diathesis and nutritional myopathy (muscular dystrophy) in chicks. Niacinamide (Vit-B3) also called niacin, is involved in enzyme systems associated with metabolism. A deficiency results in reduced weight gains, poor appetite, often a very dry skin and diarrhoea. The skin may turn a yellow colour with dermatitis and loss of hair. Posterior paralysis may also occur. The amino acid tryptophan acts as a precursor and if this amino acid is deficient there is a greater risk of niacin deficiency. Niacin plays important role in increasing the milk yield and fat percentage in the milk.

Minerals in Grogold
Manganese is important in enzyme production and the development of bone. It is also required for normal reproductive function. Deficiencies are reported to be associated with lameness, irregular oestrus, delayed sexual maturity and weak offsprings at birth.
Selenium is a highly toxic mineral but it is required in very minute amounts for normal bodily functions. Animals become anorexic with loss of hair and separation of hooves at the coronary band. Paralysis of front and hind legs is common. As the disease progresses there is liver and kidney failure.

Indications
Live stock Poultry
  • Anoestrus and infertility.
  • Decreased milk yield.
  • Supportive therapy in milk fever and prolapse.
  • Emaciation and general debility.
  • Pica and stiff gait.
  • Muscular dystrophy.
  • Rickets and osteomalacia.
  • Depigmentation of hair and wool.
  • Poor weight gain, decreased FCR
  • Thin shelled egg.
  • Eggs with low hatchability
  • Lameness in second week.
  • Low immunity.
  • Perosis in chicks.
  • Exudative diathesis.
  • Early moulting.
  • Encephalomalacia.

Regular feeding rate
Sheep and Goat 20 g. once a day
Cattle, Camel and Horse 40 g. once a day
Chicken and broiler 800 g. in 100 kg feed
Layer 400 g. in 100 kg feed.

During deficiency the dose may be doubled or as recommended by the prescriber.

Presentation
400 g. & 800 g.

Note
Many case studies have demonstrated the following benefits on regular supplementation of Grogold.Reduce the supplementation of costly inorganic phosphorus in feeds, reduce the feed cost, & increase the profit. The supplementation of Grogold can increase the assimilation efficiency of phytate phosphorus by 30-40% in pig feeds.
  • Reduce the supplementation of costly inorganic phosphorus in feeds, reduce the feed cost, & increase the profit. The supplementation of Grogold can increase the assimilation efficiency of phytate phosphorus by 30-40% in pig feeds.
  • Reduce the total phosphorus contents in feeds and reduce the excreted phosphorus through manure by 40-60%, thus reducing environmental pollution.
  • Increase the utilization efficiency of minerals, proteins and other nutrients & improve the production performance of Livestock.
  • Increase the space in feed formula to improve feed quality.
  • Reduce the risk of heavy metal poisoning and microbial pollution caused by dicalcium phosphate & bone meal, respectively.
  • Reduce the dust pollution in feed processing by reducing the supplement inorganic phosphorus.

Moulting is the process of shedding and renewing feathers. During the moult the reproductive physiology of the bird is allowed a complete rest from laying and the bird builds up its body reserves of nutrients.

Perosis (Bird Disease) A disorder of chicks, turkey poults, and young swans, characterized by enlargement of the hock, twisted metatarsi, and slipped tendons; it can be largely eliminated by adding manganese and choline to the diet.

Encephalomalacia is a nervous syndrome characterised by ataxia (incoordination of movements), backward and downward retraction of the head (some times with lateral twisting)

Exudative diathesis is a vit-E deficiency disease which occurs in chicken during the first or second month of life.The exudate usually manifest itself as a subcutaneous edema found upon the breast and abdomen.
Gromin-SE DOWNLOAD BROCHURE
A synergistic combination of minerals and vitamins

Nutritional value per 1 kg
Calcium 270 gm
Phosphorus 135 gm
Vitamin A 6,00,000 IU
Vitamin D3 1,20,000 IU
Vitamin E 150 IU
Vitamin B12 500mcg
Copper 5 gm
Cobalt 100 mg
Iron 2 gm
Selenium 20 mg

Salient features
  • Gromin SE is the latest formulation with superior pharmacodynamics as it provides synergistic combination of minerals and vitamins.
  • Calcium and phosphorus in proper ratio of 2:1
  • Gromin SE provide selenium in stabilized form.
  • Vitamins added in Gromin SE are gelatin coated and mineral stabilized.


Gromin-SE
Calcium
Calcium is the most abundant mineral element in the body; ~98% functions as a structural component of bones and teeth.( Calcium and phosphorus in bones are almost always in a ratio of 2:1 ).The remaining 2% is distributed in extracellular fluids and soft tissues and is involved in such vital functions as blood clotting, membrane permeability, muscle contraction, transmission of nerve impulses, cardiac regulation, secretion of certain hormones, and activation and stabilization of certain enzymes. When cattle are fed roughages produced on calcium-low soils, or when finishing cattle are fed high-grain diets with limited nonlegume roughage, a calcium deficiency may develop.

Phosphorus
About 80% of the phosphorus in the body is found in the bones and teeth, with the remainder distributed among the soft tissues. Adequate phosphorus is required for optimal performance in growth, reproduction, and lactation. In a phosphorus deficiency, reduced growth and inefficiency of feed conversion, decreased appetite, impaired reproduction, reduced milk production, weak and fragile bones can be expected

Iron & Copper
These are necessary for formulation of haemoglobin.

Cobalt
It is a component of vit B12 molecules thus required for the synthesis of vit B12. Deficiency causes decrease in appetite, anaemia, anoestrus, infertility and execessive lacrimation. Cobalt deficient animals are more susceptible for the parasitic infestation. Growth and production of wool and milk severely hampered in cobalt deficient animals.

Selenium
It helps in vitamin E absorption and utilization. Prevents degeneration and fibrosis of the pancreas in chicks. White muscle disease normally is seen in young calves (or lambs) and is associated with deficiencies of selenium or vitamin E, or both. Affected animals have chalky white striations, degeneration and necrosis of cardiac and skeletal muscle. In addition, paralysis of the hind limbs, and adystrophic tongue. Pigs deficient in selenium, become anorexic with loss of hair and separation of hooves at the coronary band. Paralysis of front and hind legs is common. As the disease progresses there is liver and kidney failure and the pigs become toxic

Vitamin A
Vitamin A deficiency may lead to reproductive disorders, disturbances of the eye & epithelial tissue of respiratory, reproductive, nervous, urinary and gastrointestinal. system.. Corneal lesions are usually associated with advanced vitamin A deficiency. Xerophthalmia is a degenerative condition of the eye associated with a vitamin A deficiency.

Vitamin D
It is important for proper bone growth and ossification. Deficiency lead to rickets, stiffness, weak & bent bones & posterior paralysis. Vitamin D is also required for proper calcium metabolism. Animals housed outside with access to natural, unfiltered sunlight usually have adequate levels of vitamin D3 because inactive vitamin D precursors in the skin are converted to vitamin D3, when the skin is exposed to ultraviolet (UV) light. Herbivores that have limited exposure to UV light should receive supplemental vitamin D3. An inadequate levels of vitamin D can result in nutritional secondary hyperparathyroidism, fibrous osteodystrophy, osteomalacia, cystic calculi, cloacal calculi, and rickets. Pathologic fractures, bone deformities, and soft or deformed shells may occur.

Vitamin E
It is necessary for fertility. It acts as an antioxidant. Deficiency causes muscular dystrophy, infertility.

Vitamin B12
It is required for growth, hemoglobin and red blood cell formation. deficiency of which causes dietary anemias, loss of condition and muscular weakness.

Indications
Live stock Poultry
  • Anoestrus and infertility
  • Milk fever.
  • Pica and stiff gait
  • Rickets and osteomalacia
  • Muscualar dsystrophy
  • Prolapse and haemoglobinurea
  • Thin shelled eggs.
  • Lameness in 2nd week
  • Low hatchability
  • Delayed onset of laying
  • Exudative diathesis (general oedema)
  • Muscular dystrophy

Regular feeding rate
Live stock  
Large animals 30-50 g. once a day
Small animals 10-15 g. once a day.
Poultry  
Broilers and chicks 1 kg / 100 kg feed
Layers and breeders 0.5 kg / 100 kg feed

Presentation
500 gm, 1kg, 2 kg, 10 kg & 25 kg

Note
In anoestrus & infertility – Gromin SE should be given with 4 tabs of vets cu-co for 2-3 weeks.
Lifer DOWNLOAD BROCHURE
Liquid feed supplement with Iron, calcium, B-complex, liver extract and Biotin.

Nutritional value of each 30 ml.
Ferrous gluconate 280mg
Calcium Lactate 300mg
Biotin (Vit. H) 100 mcg
Vit. B1 5mg
Vit. B2 5mg
Niacinamide 50mg
Vit. B12 10 mcg
(equivalent to B12 activity available from 1.67 ml of Liver extract)


Biotin is a functional constituent of various enzyme system necessary to prevent fatty liver & kidney syndromes. It also controls dermatitis affecting bottom of feet, corners of mouth & edges of eye lids. Biotin prevents perosis in chicks & improves hatchability.

Function of individual components :
Lifer contains iron in the form of Ferrous Gluconate, a macro-element required in trace quantity.Iron is essential for growth and increased rate

Lifer
of erythropoiesis. Iron deficiency increases the erythrocyte fragility, thereby shortening their life span and thus increased removal of RBC from circulation.

Lifer contains calcium in the form of calcium lactate, essential for strong bones and more egg production Deficiency causes osteodystrophy. Calcium is co-factor for activation of co-agulation factors.

Biotin (Vit-H) in Lifer has a significant effect on carbohydrate metabolism, fatty synthesis, amino acid deamination, purine synthesis and nucleic acid metabolism.

Vitamin B1 (Thiamine) in lifer acts as coenzyme for transketolase, necessary for normal fatty acid and cholesterol production, thereby affecting neuronal membrane synthesis and integrity. It is also necessary for the synthesis of the principal neurotransmitter, acetylcholine, and for the passive transport of sodium across excitable membranes.

Vitamin B2 (Riboflavin) plays a key role in the metabolism of carbohydrates, amino acids and fats and is central to the processes of mitochondrial respiration and oxidative phosphorylation.

Niacinamide in Lifer is essential for normal carbohydrate metabolism.

Lifer contain Vitamin B12 (cynocobalamine), deficiency of which causes dietary anemias, loss of condition and muscular weakness.

Salient features
  • Lifer is essential for growth, erythropoiesis and to activate co-agulation factor
  • Lifer is an important supportive prescription in the treatment of Liver Fluke infestation.
  • Lifer plays improvement role in carbohydrate, fat & protein metabolism.
  • Lifer helps neuronal membrane synthesis & integrity.
  • Lifer is essential for synthesis of principal neurotransmittor i.e. acetyl choline

Indications
  • Anaemia.
  • Anorexia, cessation of growth, loss of condition, muscular weakness.
  • Prevention of rickets, osteomalacia, degenerative arthropathy.
  • Poor growth, diarrhoea, loss of hair, circumoral skin lesion and excessive lacrimation.
  • Lifer supports early recovery during treatment of various infections and blood loss.
  • Lifer for prevention and control of stress.
  • Paralysis of hind legs in calves.
  • Lifer for increased milk production.

Horse For treatment of britle and weak hoof lesion in horses. Osteodystrophia fibrosa.
Sheep For marked dental abnormalities.
Pig In premature parturition / still birth, anemia in piglets and for rapid growth.
Dogs In flaky dermatitis, muscle weakness, ataxia (in-coordination in movements) and occular lesion.
Poultry Thin shelled eggs, poor hatchability and reduced egg production.

Feeding rate
Cattle, Horse and Camel 50 ml twice daily
Calf, Foal, Sheep, Goat and Pig 25 ml twice daily
Dog 10 ml twice daily
In poultry for each 100 birds  
Chicken 10 ml twice daily
Grower and Broiler 20 ml twice daily
Layer 50 ml twice daily

Presentation
200 ml, 500ml, 1 lt. & 5 lt.
Profimin Forte DOWNLOAD BROCHURE
A complete & perfect Mineral mixture (chelated)
Enriched with vitamins, aminoacids & antioxidants


To ensure sound Health, optimum Production, normal Reproduction & strengthened immunity.
Profimin forte is a mixture of minerals, vitamins and aminoacids fortified with chelated minerals, vitamin–C, biotin, protein hydrolysate and BHT (butylated hydroxyl toluene) for regular supplementation in the animals and fish feed for higher profits.
These minerals, vitamins and aminoacids are required for health, production and reproduction. In lactating animals, these components are secreted in milk so need to be supplemented regularly.

Nutritional value per kilogram
Each 10 ml contains
Vit-A 7,28,000 IU Vit D3 1,45,600 IU
Vit E 250mg Vit C 2000mg
Niacin(Vit B3) 1000mg Biotin FG(Vit-H) 100mg
Calcium 25.5 %, Phosphorus 12.75%
Copper 1200mg Cobalt 150mg
Iron 1560mg Iodine 325mg
Manganese 1560 mg Magnesium 6240mg
Zinc 9600mg Selenium 10mg
Potassium 100mg Sodium 6.14 mg
Sulphur 0.72% L-Lysine mono HCL 4500mg
DL-Methionine 1500mg Protein Hydrolysate 3000mg
Butylated Hydroxy 100mg  
Toluene  


Profimin Forte
Salient Features
  • It increases milk, milk fat and solid not fat.
  • It contains lysine and methionine (amino acids) in ratio 1:3, similar to found in body tissues, rumen bacteria and milk
  • Provides maximum bioavailability of minerals as it contains chelated minerals. The theory is that a neutral chelated molecule will be more completely absorbed than a non-chelated form.
    Use of chelates in animal nutrition (Main objectives)
    Reduction of antagonism, interference and competition among minerals.
    Improve the bioavailability of minerals.
    Health improvement (immune status, functional nutrition)
    Over all animal welfare.
    Improvement in animal produces quality (meat, milk, egg, wool, etc.)
    Reduces degenerative effect of trace minerals on vitamins in premixes and feed.
    Protect environment by reducing metal pollution.
  • Ensures exceptional feed processing stability of vitamins and minerals.
  • Takes care of negative energy balance after parturition. (negative energy balance – after parturition energy requirements are increased so profimin forte prevents animal in negative energy state.)
  • It contains protein hydrolysate that improves nitrogen retention. Nitrogen is a component of proteins.
  • It regulates the oestrus cycle with improved conception rate.
  • Reduces the incidence of mastitis, ketosis, milk fever, fatty liver, retained placenta and abortion.
  • It contains vitamin Biotin required for cellulose digestion in the rumen and for hoof health (biotin required for keratin layer of the foot) thereby prevents lameness by prevention formation of cracks in the hoof wall.
  • It contains antioxidants (vitamin A,C,E, minerals – selenium, copper and zinc)
    1. that stabilize highly reactive free radicals.(free radicals are the atoms or group of atoms with an unpaired number of electrons and can be formed when oxygen reacts with certain molecules. Once formed, these highly reactive free radicals can start a chain reaction. They damage cells by damaging components of cells like DNA)
    2. enhance immunity by maintaining the functional and structural integrity of important immune cells. (cells that fight against infections)
    3. reduce circulating glucocorticoids (stress hormones) that minimize stress and enhance performance.
    4. possess antibacterial and antiviral properties.:- vitamin-c has direct antiviral properties by stimulating interferons production and enhance bactericidal functions of neurtophils and macrophages. Vitamin –E plays a role in resistance to viral infection. Vitamin –A deficiency causes decreased phagocytic activity in macrophages and neutrophils (vety pharmacology by Adams 8th edition)
    5. Butylated hydroxyl toluene BHT- antioxidant property of BHT protects feed ingredients from oxidative decomposition.
Calcium
It is the most abundant mineral element in the body; ~98% functions as a structural component of bones and teeth.( Calcium and phosphorus in bones are always in a ratio of 2:1). The remaining 2% is distributed in extracellular fluids and soft tissues and is involved in such vital functions as blood clotting, membrane permeability, muscle contraction, transmission of nerve impulses, cardiac regulation, secretion of certain hormones, and activation and stabilization of certain enzymes. When cattle are fed roughages produced on calcium-low soils, or when finishing cattle are fed high-grain diets with limited nonlegume roughage, a calcium deficiency may develop.

Phosphorus
About 80% of the phosphorus in the body is found in the bones and teeth, with the remainder distributed among the soft tissues. Adequate phosphorus is required for optimal performance in growth, reproduction, and lactation. In a phosphorus deficiency, reduced growth and inefficiency of feed conversion, decreased appetite, impaired reproduction, reduced milk production, and weak, fragile bones can be expected..

Iron & Copper
These are necessary for formulation of haemoglobin.

Cobalt
It is a component of vit B12 molecules thus required for the synthesis of vit B12. Deficiency causes decrease in appetite, anaemia, anoestrus, infertility and execessive lacrimation. Cobalt deficient animala are more susceptible for the parasitic infestation. Growth and production of wool and milk severely hampered in cobalt deficient animals.

Iodine
Iodine is required in the production of thyroxin hormone from the thyroid gland, deficiency of which causes goiter. Iodine deficiency may be seen in cattle that are consuming an “adequate” level of iodine if they are also consuming fairly large quantities of crops of the cruciferae family, such as mustard, turnips or cabbage. Affected cows may give birth to hairless calves Deficiency also causes anoestrus condition in dairy animals, still birth or weak at birth or abortions, infected navals, prolonged gestation periods.

Manganese
It is essential for normal reproduction & growth. Ataxia is found predominantly in calves and is most often attributed to a chronic manganese deficiency. Deformities of affected animals include weak legs and pasterns, enlarged joints, stiffness, twisted legs, general weakness, and reduced bone strength.

Selenium
Blind staggers is a sign of acute selenium toxicity. Affected cattle show dullness, ataxia, rapid weak pulse, labored respiration, diarrhea, and lethargy; the head is lowered and the ears droop. Death is due to respiratory failure. In less severely affected cattle, there is lameness; loss of vitality; loss of appetite; emaciation; deformed, cracked, and elongated hooves; loss of hair from the tail; and liver cirrhosis.

White muscle disease normally is seen in young calves (or lambs) and is associated with deficiencies of selenium or vitamin E, or both. Affected animals have chalky white striations, degeneration, and necrosis of cardiac and skeletal muscle. In addition, paralysis of the hindlimbs, a dystrophic tongue.

Magnesium
Hypomagnesemic tetany (grass tetany) is due to a relative deficiency of magnesium—relative because the dietary magnesium may be tied up in such a manner that it is not available. Among the signs of experimentally produced magnesium deficiency in both young and mature cattle are anorexia, hyperemia, greatly increased excitability, and calcification of soft tissues in a chronic deficiency condition. An affected animal exhibits convulsions, falling on its side with its legs alternately extended and relaxed. Death may occur during the convulsions. Frothing at the mouth and profuse salivation are evident. The signs appear to progress much more rapidly in adult cows.

Zinc
Dermatitis can be seen in both calves and mature cows due to a zinc deficiency, usually in the range of <10 ppm (parts per million) of dietary zinc. Generally, it is most severe on the legs, neck, and head and around the nostrils. Wounds are slow to heal. Additional signs associated with zinc deficiency include decreased testicular growth, listlessness, development of swollen feet with open scaly lesions, and alopecia.

Potassium
Potassium is required for the maintenance of acid base balance and osmotic relation. Deficiency causes decreased feed consumption and slow growth.

Sulphur
It is required in synthesis of sulphur containing amino acid in rumen. Deficiency causes protein deficiency and poor performance.

Sodium
It is required in control of body fluid concentration,control of body fluid pH, nerve and muscle activity. Deficiency disrupts nerve and muscle function, loss of electrolyte balance.

Vitamin A
Its deficiency may lead to reproductive disorders, disturbances of the eye & epithelial tissue of respiratory, reproductive, nervous, urinary and gastrointestinal. system.. Corneal lesions are usually associated with advanced vitamin A deficiency.
Xerophthalmia is a degenerative condition of the eye associated with a vitamin A deficiency.

Vitamin D
It is important for proper bone growth and ossification which may lead to rickets, stiffness, weak & bent bones & posterior paralysis.

Vitamin E
It is necessary for fertility. It acts as an antioxidant. Deficiency causes muscular dystrophy, infertility. Chicks deficient in vit E shows signs of encephalomalacia(out starched legs with toes flexed), exudative diathesis (oedema of the inside thighs under the skin), embryonic mortality and reduced hatchability.

Vitamin–C
It acts as an antistress factor. It is required for different biochemical reactions mainly related to the synthesis of intercellular substances including collagen eg. tooth , bone. It increases the immunity of the body.
Deficiency causes digestive disturbances andheat stress.

Niacinamide (Vit-B3)
Niacinamide in profimin forte is essential for normal carbohydrate metabolism.

Biotin
Biotin is a functional constituent of various enzyme system necessary to prevent fatty liver & kidney syndromes. It also controls dermatitis affecting bottom of feet, corners of mouth & edges of eye lids. Biotin prevents perosis in chicks & improves hatchability.

Protein hydrolysate
It is  a mixture of amino acids prepared by splitting a protein with acid, alkali, or enzyme; used as a nutrient replenisher.

Lysine (Essential aminoacid)
Ensures adequate calcium absorption and maintains a proper nitrogen balance in adults; helps form collagen (which makes up cartilage and connective tissue); aids in the production of antibodies.

Methionine(Essential aminoacid)
A powerful anti-oxidant and a good source of sulfur, which prevents disorders of the hair, skin, and nails, assists the breakdown of fats, thus helping to prevent a buildup of fat in the liver and arteries, that might obstruct blood flow to the brain, heart, and kidneys; helps to detoxify harmful agents such as lead and other heavy metals; helps diminish muscle weakness; prevents brittle hair; protects against the affects of radiation; it promotes the excretion of estrogen; reduces the level of histamine in the body which can cause the brain to relay wrong messages.

Butylated hydroxyl toluene (BHT)
Antioxidant property of BHT protects feed ingredients from oxidative decomposition.

Feeding rate
Cattle and buffalo – 25 g. daily or 1 kg. in 110 kg of feed.
Calf - 10 g. daily
Fish - 1 kg. in 110 kg. feed

Presentation
1 kg., 5 kg. and 25 kg.

Note

Trial
Profimin forte @ 25 g. daily for two weeks was fed to a group of lactating cattle and parameters were recorded on 7th and 14th day.
On 7th day a mean increase of 11.97 % fat and 14.57 % SNF.
On 14th day a mean increase of 17.89% fat and 21.28 % SNF.

Factors affecting farmer’s profitability which can be taken care by regular feeding Profimin Forte in livestock & poultry feed.
  • Decrease in milk yield.
  • Double loss when animal become sick., one in terms of treatment cost and another in milk yield.(production)
  • When animal is in stress, performance is decreased.
  • Feed components may be damaged due to oxidative decomposition of fat containing raw materials, feed fats and mixed feed so there may be loss of active ingredient.

Hair coat roughness
is related to deficiency of energy, phosphorus, salt, vitamin A, cobalt, or copper.

Retained placenta
The nutritional causes of retained placenta appear to be rather complex and include deficiencies of selenium, vitamin A, copper, and iodine. The incidence increases with parturient hypocalcemia.
Toxiliv DOWNLOAD BROCHURE
Hepatotonic

Compositon
Each 10 ml contains
Choline chloride 2000mg
Protein Hydrolysate 50mg
Yeast Extract 40mg
Inositol 35mg
Niacin 24mg
DL Panthenol 2.5mg
Vitamin B12 3.3 mcg
(equivalent to vitamin B12 available from 0.55 ml of liver extract 1:30)

Salient Features
  • Toxilive is a feed supplement to boost liver functions.
  • Toxilive contains choline chloride,yeast extract, niacin, DL panthenol and inositol.
  • Choline is required for the synthesis of neurotransmitter acetylcholine.
  • Prevents pathological changes and the accumulation of of fat in liver and kidneys.
  • It facilitates lipoprotein synthesis by liver and prevents lipidosis.
  • Improves physique and growth rate of live stock and poultry.
  • Helps in normal carbohydrate metabolism.
  • It helps to increase peristalsis in atony and paralysis of the lower intestine and to help relieve gas retention and abdominal distension.
  • Toxilive as supportive therapy in liver dysfunctions due to hepatic diseases, parasitic diseases, aflotoxins, drugs etc.
  • Toxilive improves feed intake, carbohydrate metabolism and milk fat percentage.
  • Toxilive improve growth and livability in livestock and poultry.
  • Toxilive as supportive therapy in diarrhea and constipation due to hepatic disease.

Toxiliv

Action of individual ingredient

Choline chloride
Choline is one kind of vitamin It is the main element of lecithin. It is of great importance for the growth, breeding and nutrition of fowls and livestock. Because young fowls and livestock lack the function of synthesizing choline by themselves, the required choline is all from feed supply. Though choline exists widely in most natural foods, the choline content can not meet the demand for animals’ growth. Thus, it is necessary to add choline in the feed to ensure their rapid and healthy growth.

Choline chloride can help to improve the physiological function of the resynthesis and transformation of amino acid. It has functions of preventing pathological changes and the accumulation of fat in livers and kidneys. Thus it can improve the physique, premonition and growth rate of fowls and livestock, it can also improve the survival rate of newborn pigs, as well the growth and survival rate of fishes.

Choline is essential as a component of lecithin, a key phospholipids for maintaining cell membrane structure and function. It plays an important role in lipid metabolism, facilitating lipoprotein synthesis by the liver and preventing hepatic lipidosis. Choline is required for the synthesis of the neurotransmitter acetylcholine

Signs attributed to choline deficiency in ruminants are restricted to those with heavy growth or lactational demands. Feed intake and milk fat percentage were increased following choline supplementation in lactating cows. Choline deficiency in pigs is characterized by reduced growth rate, poor conformation, incoordination, joint rigidity, reproductive problems and hepatic lipidosis. Choline deficiency in puppies and kittens has been characterized by decreased growth and hepatic lipidosis. Choline deficiency in poultry causes growth retardation, perosis, fatty liver and decreased egg production.

Protein Hydrolysate
Protein Hydrolysate consists of amino acids and short chain peptides, which represent the approximate nutritive value equivalent to suitable protein from which it has been derived by enzymatic hydrolysis. It provides a better source of easily assailable mixture of amino acids in a concentrated form.

In the Soviet Union protein hydrolysates are used for the treatment of hypoproteinaemia, exhaustion and intoxications, particularly in young farm animals (e.g. calf diarrhoea, white muscle disease).

Yeast
Yeasts are unicellular, although some species with yeast forms may become multicellular through the formation of a string of connected budding cells known as pseudohyphae, or false hyphae as seen in most molds. The yeast species Saccharomyces cerevisiae has been used in baking and fermenting alcoholic beverages for thousands of years. The term "yeast" is often taken as a synonym for S. cerevisiae.

Yeast is used in nutritional supplements, where it is often referred to as "nutritional yeast". It is a deactivated yeast, usually Saccharomyces cerevisiae. It is an excellent source of protein and vitamins, especially the B-complex vitamins, whose functions are related to metabolism as well as other minerals and cofactors required for growth.

Inositol
Inositol, an isomer of glucose, has traditionally been considered to be a vitamin B substance although it has an uncertain status as a vitamin. Sources of inositol include whole – grain cereals, fruits and plants, in which it occurs as the hexaphosphate, phytic acid.

Inositol appears to be involved physiologically in lipid metaboloism and has been tried, with little evidence of efficacy, in disorders associated with fat transport and metabolism.

Niacin
Niacin or its active form nicotinamide, is a metabolic essential for all animals but is a dietary essential only under special conditions. Dog may experience niacin deficiency if fed improperly.
Niacin is converted in the body to two similar coenzymes, nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), that are integral to hydrogen transfer in all major metabolic pathways. Although they are structurally similar, they serve different functions. NAD is more closely associated with transfer of hydrogens to oxygen in oxidative metabolism. NADP is more commonly associated with hydrogen transfer in synthetic reactions in the body, particularly reductive steps in lipid synthesis.

Nicotinic acid is reported to have a favorable effect on blood lipid profiles, raising high density lipoprotein (HDL)- cholesterol and lowering low – density lipoprotein (LDL)- cholesterol..

Black tongue in dogs is the classic disease associated with niacin deficiency. In most species, oral lesions affecting the mucosa give a blackened appearance and result in a thick saliva, malodorous breath , and ulcerative lesions. Diarrhea and anemia also are common as well as the usual signs of vitamin deficiency such as in appetence and poor growth. Corn and cereal grains contain fairly adequate quantities of niacin, but the vitamin is in a bound and unavailable form. Swine and poultry on intensive production with high concentrate cereal grains or corn should receive supplemental niacin or nicotinamide.

Ruminants do not require an exogenous source of either niacin, nor do horses ( Robinson and Slade 1974). Dogs develop the classic animal deficiency syndrome. Swine and poultry often require additional niacin. The specific requirements vary with type of production and amount of precursor available.

Niacinamide: proven benefits
  • Maintains normal function of skin, nerves, digestive system.
  • Corrects niacin deficiency.
  • Dilates blood vessels.
  • Control ketosis, stimulate rumen protozoa.

What this vitamin does:
  • Aids in release of energy from foods.
  • Helps synthesis of DNA.
  • Becomes a component of two co-enzymes (NAD and NADP), which are necessary for utilization of fats, tissue respiration, production of sugars.

DL Panthenol
DL-Panthenol is a stable lit racemic mixture of D-Panthenol and L-Panthenol. The human body converts D-Panthenol to Pantothenic Acid (Vitamin B5), a natural constituent of healthy hair and a substance present in all living cells. Only D-Panthenol is converted to Vitamin B5 and not the L-Panthenol. So the racemic D,L-Panthenol has only half of the physiological activity of D-Panthenol.

Metabolic functions Pantothenic acid functions mainly as CoA, which facilitates reactions of carboxylic acids catalyzed by such enzymes as pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, fatty acid synthetase, propionyl CoA carboxylase, and acyl CoA synthetase (Mc Dowell 1989e). It is necessary for the activation of acetic acid, as aceyl CoA for entry of carbon skeletons into the TCA cycle, synthesis of fatty acids and cholesterol, and the production of the neurotransmitter acetylcholine. As acyl carrier protein, it functions as a carrier for intermediate- chain acyl groups in the synthesis of fatty acids (Mc Dowell 1989e)

Signs of deficiency
Pentothenic acid deficiency in animals is characterized predominantly by disorders related to its prominent role in intermediary metabolism. Pantothenic acid deficiency is uncommon in adult ruminants and horses, whose needs are provided by ruminal and large- intestinal microorganisms, respectively. ( Cunha 1991e).
Clinical signs of deficiency in growing calves have been produced experimentally, including anorexia, poor growth, diarrhea, rough hair coat, and particularly a scaly dermatitis around the eyes and muzzle. Many practical swine diets, particularly those based on corn or soybean meal, contain marginal level of pantothenic acid. Deficiency in pigs is characterized by anorexia, poor growth, hemorrhagic diarrhea, dermatitis, and locomotor disorders, particularly affecting the hind limbs (Mc Dowell 1989e). the hind limbs progressively show tremors, spasticity, and an axaggerated gait ( goose stepping), due to demyelinization of nerves in the dorsal root ganglia (Blair and Newsome 1985). Pantothenate deficiency causes inappetence, weight loss or growth depression, lowered antibody responses, and hind limb spasticity in dogs, and hepatic lipidosis in kittens (NRC 1985,1986; McDowell 1989e). Pantothenic acid deficiency in poultry produces dermatitis, hperkeratosis, broken feathers, and decreased growth rates as well as reduced egg production and hatchability (McDowell 1989e).

Dietary requirement, indications and use
Intrinsic factors
Breed and strains differences in pantothenic acid requirements have been documented in pigs, resulting in the need for up to 50% increases in supplementation ( McDowell 1989e). In adult ruminants and horses, pantothenic acid synthesis by gastrointestinal microflora is adequate under resting conditions, but as is the case for other species, requirements increase with stress, growth, gestation, or lactation, thereby necessitating supplementation. The urinary excretion of pantorhenate may increase in polyuric renal deseases, there`by increasing the dietary requirement.

Extrinsic factors
Dietary fat and protein intake can affect pantothenic acid requirements, as can ascorbic acis, biotin, and vitamin B12 levels ( Mc Dowell 1989e). Increased fat intake necessitates greater pantothenate for CoA synthesis and lipid metabolism, while high dietary protein apparently has a sparing effect on pantothenate requirements. Vitamin B12 deficiency increases pantothenate requirements, perhaps by trapping more as CoA – conjugated intermediates in the aberrant metabolism of propionic acid. Stress and other dietary factors increase patothenic acid requirements as well. Gastrointestinal diseases may impair enteric flora pantothenate synthesis and subsequent absorption. Oral antibiotics also increases its dietary requirement, by inhibiting normal enteric microflora production.

Vitamin B12 (cyanocobalamin)
Vitamin B 12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis and energy production. Cyanocobalamin ( Vit. B 12) is a cobalt –containing vitamin required by cells throughout the body for conversion of ribose nucleotides into deoxyribose nucleotides, a mojor step in the formation of deoxyribonucleic acid (DNA). Thus it is an essential nutrient for nuclear maturation and cell division and deficiency of this vitamin results in generalized depression of cellular development and tissue growth.

Because the erythropoietic centres of the bone marrow are among the most rapidly growing and proliferating tissues, inadequate amounts of cyanocobalamin are sepecially manifested by decreases in erythrocyte production.

Requirement
Adult ruminants are not dependent on a dietary source of this vtamin because ruminal microflora synthesize all the required supplies of cyanocobalamin. How ever dietary source of cobalt is required by ruminal organism to synthesize vit B12 and cobalt shortage can result in an indirect deficiency of vitamin. Enteric bacteria of many non-ruminants spp. can also synthesize cyanocobalamin, thereby reducing the need for dietary source. How ever vitamin B12 deficiency may still result from inadequate absorption of the vitamin from the digestive tract. In adult ruminants and horses vit B12 synthesis by gastrointestinal flora is adequate under resting conditions but as is the case for other spp. requirement increases with stress, growth, gestation or lactation, thereby necessitating supplementation. The more rapid the rate of growth or the greater the level of production, the greater the need for vit B12. The urinary excretion of vit B12 may increase in polyuric renal diseases, thereby increasing the dietary requirement.
Gastrointestinal diseases may impair enteric microbial vit. B12 synthesis and subsequent absorption. Oral antibiotics may also increase its dietary requirement by inhibiting normal enteric microfloral production.

Absorption and storage
Vit B12 is absorbed almost exclusively in the ileum, in a carrier- mediated process with a specific receptor protein located on the microvillus border of the enterocytes. Following its transport from the enterocytes to the portal blood, vit B 12 is bound to protein called transcobalamins, which are synthesized by the liver and facilitate transport and storage of the vitamin. Liver contains much of the body stores and half life has been reported to be as long as one month .

Indications
  • As supportive therapy in hepatic dysfunction due to hepatic disease. aflotoxins, microtoxins, drugs etc.
  • Lipidosis
  • Liver dysfunction due to parasitic diseases.
  • Diarrhea or constipation due to hepatic disease.
  • To improve egg production, hatchability and weight gain.
  • To improve feed intake and milk fat percentage.
  • To improve growth and livability in livestock and poultry.

Dosage

Calf, Sheep and Dog: 3-5 ml daily for 7-10 days
Cattle, Horse and Camel 20 ml daily for 7-10 days.
Poultry  
Chicks 0.5 ml per litre of drinking water
Growers and Broiler 0.5 ml per litre of drinking water
Layers and Breeders 1.0 ml per litre of drinking water.

Presentation
1 lt. and 5 lt.
Vetral DOWNLOAD BROCHURE
(A powerful antisress liquid supplement for cattle and poultry)

Composition
Vitamin A 12,000 I.U.
Vitamin D3 6,000 I.U.
Vitamin E 48 mg
Vitamin B12 20 mcg

Detail of individual ingredient
Vitamin A : deficiency may lead to reproductive disorders, disturbances of the eye & epithelial tissue of respiratory, reproductive, nervous, urinary and gastrointestinal system.. Corneal lesions are usually associated with advanced vitamin A deficiency.
Xerophthalmia is a degenerative condition of the eye associated with a vitamin A deficiency
Vitamin D : A major function and possibly the sole function of vit.D is related to its role in the intestinal and cellular absorption of calcium. Calcium, phosphorus and vit D are closely interrelated physiologically. A deficiency of any one or a severe imbalance of the three may lead to rickets in young or osteomalacia in mature animals, stiffness, weak & bent bones & posterior paralysis.
Vitamin E - It is necessary for fertility. It also acts as an antioxidant. It is required for better immune response. Deficiency causes muscular dystrophy, infertility. Chicks deficient in vit E shows signs of encephalomalacia(out starched legs with toes flexed), exudative diathesis (oedema of the inside thighs under the skin), embryonic mortality and reduced hatchability.
Vitamin B12 is required for growth, hemoglobin, red blood cell formation, embryonic development and feathering (in poultry). Deficiency of vitamin B12 causes dietary anemias, loss of condition and muscular weakness. In poultry deficiency effects hatchability.


Vetral
Recommendations
  • To prevent and overcome stress.
  • To build resistance against various diseases.
  • To accelerate production and growth.

Feeding rate
Poultry : to be given in water or feed for 5-7 days
Chicks 50 ml per 1000 birds
Growers 70 ml per 1000 birds
Layers 100 ml per 1000 birds
Livestock
Sheep and Goat 10 ml daily
Cattle, Camel and Horse 20 ml daily
Pets 3-5 ml daily.

Presentation
30 ml, 60 ml, 100 ml, 500 ml and 1000 ml.
Vets Cu-Co DOWNLOAD BROCHURE
(Perfect copper and cobalt tablet)

Formulation
Each tablet contains
Copper Sulphate 200 mg
Cobalt Sulphate 20 mg

Action of individual ingredient
Copper sulfate
Copper sulfate occurs as a blue crystalline powder prepared from copper oxide. Its chemical formula is CuSO45H2O. It is soluble in water and glycerine. Copper Sulphate is an animal remedy (dietary copper supplement) to prevent and treat copper deficiency in livestock. Copper is an essential element in many enzymes that are essential for the normal functioning of the body. Copper is involved in transport of minerals in the blood, development of many body tissues, production of pigments and in the normal function of the immune system. Copper is also an important part of the antioxidant system, which protects the body against damaging chemicals. As copper is involved in so many places, copper deficiency has been linked to many problems. However the most commonly linked problem in adult dairy cattle is poor fertility.

Its deficiency is reported to be responsible for early embryonic death, increased chances of retained placenta and necrosis of placenta and low fertility associated with delayed or depressed estrus. In addition to this, proper copper supplementation is must for quality semen production. Copper treatment is re- ported to improve conception rate as the copper treated cow require 1 service and the untreated cow require 1. 15 services per conception.


Vets Cu-Co
In bovine copper deficiency can occur when diets are inadequate in copper or contain excess amounts of interfering substances, particularly sulfates and molybedenum. Profuse watery diarrhea with poor weight gain is a common syndrome seen in ruminants with copper deficiency.

Cobalt sulphate
Cobalt sulphate is the dietary cobalt supplement. It is a component of vit B12 molecules thus required for the synthesis of vit B12. Cattle do not depend on dietary vitamin B12 because ruminal microorganisms can synthesize it from dietary cobalt. In cattle, therefore, a cobalt deficiency is a relative vitamin B12 deficiency Deficiency causes decrease in appetite, loss in weight, anaemia, fatty degeneration of the liver, anoestrus, infertility and execessive lacrimation. Cobalt deficient animals are more susceptible for the parasitic infestation. Growth and production of wool and milk severely hampered in cobalt deficient animals.

Infertility is likely to arise as secondary consequences of debility conditions such as sever cobalt deprivations through reduced general metabolism. Delay in onset of puberty, delay uterine involution and decreased conception rate and sub optimal conditioning of the offspring are noted in cobalt deficiency.

Recommendations
  • To maintain the normal physiology of reproductive system.
  • To prevent copper and cobalt deficiency disorders.

Feeding rate
Cattle and Horse 4 tablets daily for 2-3 weeks.
Camel 6 tablets daily for 2-3 weeks
Sheep and Goat 2 tablets daily for 2-3 weeks.

Presentation
50 tablets.